Prevalence of elevated antithyroid antibodies and antinuclear antibodies in children with immune thrombocytopenic purpura

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Prevalence and clinical significance of elevated antiphospholipid antibodies in patients with idiopathic thrombocytopenic purpura.

Antibodies against phospholipid antigens (APA) have been demonstrated in idiopathic thrombocytopenic purpura (ITP), but their clinical and pathogenetic significance has remained elusive. In this study we analyzed the prevalence and clinical features of ITP patients with elevated APA. In addition, we prospectively evaluated APA levels after treatment with corticosteroids and compared them with p...

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Platelet antibodies of the IgM class in immune thrombocytopenic purpura.

The clinical course and response to therapy of patients with immune thrombocytopenic purpura (ITP) are not completely determined by the level of IgG present on the platelet surface. It is possible that antibodies of other immunoglobulin classes also play a role in platelet destruction in some of these patients. Therefore, we studied 175 patients with ITP for the presence of IgM anti-platelet an...

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High Prevalence of Antinuclear Antibodies in Children with Thyroid Autoimmunity

BACKGROUND Antinuclear antibodies (ANA) are a hallmark of many autoimmune diseases and can be detected many years before disease onset. Autoimmune thyroid diseases (AITD) are frequently associated with other organ- and non-organ-specific autoimmune disorders. Objectives. To assess the prevalence of ANA in pediatric patients with AITD and their clinical correlations. METHODS Ninety-three conse...

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Prevalence and clinical significance of the positive antinuclear antibody in children with idiopathic thrombocytopenic purpura

Received :30 May 2008, Revised :5 August 2008, Accepted :3 September 2008 Address for correspondence :Young Tak Lim, M.D. Department of Pediatrics, Pusan National University College of Medicine, Amidong 1-Ga, Seo-Gu, Busan, Korea Tel :+82.51-240-7298, Fax:+82.51-248-6205 E-mail :[email protected] 원인이다 1-3) . 면역학적 혈소판 감소는 ITP 이외에도 자가면역 용 혈빈혈, 전신홍반루푸스(SLE) 등과 같은 자가면역질환에서도 동 반될 수 있는데, 특히 SLE에서는 진단...

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Acute Immune Thrombocytopenic Purpura in Infants

Abstract Objective Immune thrombocytopenic purpura (ITP) manifests as an easy bruising or extravasation of blood from capillaries into skin and mucous membranes. The characteristics of acute ITP in infants have rarely been described. In order to better understand acute ITP in infants, the characteristics of the disease at this age group was investigated. Material and Methods The present des...

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ژورنال

عنوان ژورنال: American Journal of Hematology

سال: 2005

ISSN: 0361-8609,1096-8652

DOI: 10.1002/ajh.20299